Erica Noughton
Julia McNamara gets a surprise visit from her glamorous mother, successful child psychology author Dr. Erica Noughton, who has various reasons to want plastic surgery and insists that Sean should operate her; that even worsens his worries about an unsteady hand, and the specialist tells him it's a fashionable psychosomatic condition without a medical cure. Christian wrestles with his instincts- while resenting Gina Russo emotionally blackmailing him with her halfbreed baby, he is determined to become a good father, but swears to keep his mundane (sex-)life, so he looks for a nanny and hires Linda, the candidate with the sexiest 'fringe-benefits', but finds she's neglecting the child... Meanwhile the doctors operate on Libby Zucker, whose face is so horrible she'll need at least five major, risky operations and is most uncertain in her 'steady' relationship with attractive Chad Myers who she knows to have affairs.
Christian Troy
Christian was enjoying sex with a young model, but an allergy caused her to sneeze so her butt crushing down broke the Casanova's killer face's nose, which must be operated. Sean hoped his anxiety was over after mother in law Erica Noughton's operation, but it suddenly returns during pro bono surgery on Mr. Unger, who nearly gets butchered. Matt is interrogated after the police arrested his mate Henry in the Cara case; he denies to know anything. After a visit from Henry's shocked father, Sean suspects the truth, but Matt still denies any part in the car hit. In Dr. Monica Jordan's waiting room, Christian meets adolescent patient Calvin Murray, who says his third nipple prevents any sex life, agrees a male doctor is less embarrassing, and is eager for the gorgeous girls in Dr. Troy's waiting room. When Sean finds out Christian booked another surgeon and attacks him, he gets reminded of his list of grave errors and looses confidence again, handing the scalpel to Christian for the nipple job. Erica explains to Julia how parents, unable to accept their own failing, unconsciously transfer their ambition to their children, who thus come under excessive stress, which probably caused Matt and Henry to go overboard. Then Sean tells her his nervous disaster. Christian cheerfully stripped for Dr. Jordan who was to check him for melanoma, but was told his love handles need preventive action at age 40; to re-boost his self-confidence, he demands his next 'ride' to call him sexy, but even Gina finds that too weird and tells him he's becoming as ugly outside as inside. Henry tells Matt at a prison visit the incessant pressure was what got to him, he snatched when Cara rejected him and now fears to be raped in jail. Frustrated he operates on his own nose in front of the mirror- now he realizes and Sean sees what a shaky second can do to a surgeon; terrified Sean must fix the face of their common future, without general anesthetic so the patient can verbally assist and boost his confidence, which works.
Manya Mabika
Manya Mabika, a Somalian model, wants the surgeons to give her an orgasm by reverting her traditional female circumcision as a girl, even if the experimental technique for an artificial clitoris is highly unreliable. Macho Christian proves a far better 'parent' for Wilbur then his nymphomaniac mother Gina; when he refuses to have a baby with her, she uses Wilbur as blackmail leverage. Sean and Julia have good sex, but he cannot accept she doesn't get an orgasm. Patient Elias Perri has absolutely no body-hair, and is pushed by his life-coach, Ava Moore, to try a donor-hair transplant to erogenous zones. Sean makes an appointment for Julia with Ava, who gets into a row on the value of therapy with Julia's mother, Dr. Erica Noughton. Once she has her fake clitoris, Maniya asks Dr. Troy to be her 'true healer' in bed- when she gets no orgasm, he insists with Sean to revise her clitoris, but all it really takes is a lesson in female self-pleasing by Liz. Christian is shocked to find Gina has Sexaholics lined up for 'hetero-insemination' to give Wilbur a sibling.
Mrs. Grubman
As Julia and Sean's daughter, Annie, faces puberty, they must both face the harsh realization of maturity and deal with their own issues about getting older. When Gina tells Christian he can no longer be involved in Wilbur's life, Christian is forced to reach out to an old flame in order to build a case to gain sole custody of Wilbur.
Joel Gideon
Now both biological parents have teamed up to demand the court full and exclusive custody over 'his' baby, Christian Troy is ready to throw in the towel- but for once worst-mother-ever Gina Russo motivates him positively, so they still engage the probably hopeless legal fight. While holding and talking on his cell phone while he is driving at the same time, Sean McNamara causes a serious car accident, but without serious harm, except that his attitude towards life is shocked. He now wants to taste life to the full, and first accepts an offer to earn a luxury car by advising crash dummy tests with a corps; next he seeks adventure, but when he goes as far as to encourage Matt, who shows still to love him as his daddy, to eat a potentially lethal sushi in a Japanese restaurant, Julia walks out with his offspring. Joel Gideon is a patient whose love of danger in mountain-climbing caused him to get such bad frost bite that a facial zone including his nose is now dead tissue, and is determined to return to the same mountain after his reconstructive surgery.
Bobbi Broderick
Roberta 'Bobbi' Broderick, a ripe lady, wants plastic surgery to compete with younger women for her dream job, selling clothes. Julia sends Matt for therapy to life coach Ava Moore, but she abuses trust games to seduce the teenager; uncle Christian must bail him out after jerking off outside her window; she won't be told off, threatens to disclose he's the biological father and demands free botox. Allegra Calderello has her burned lips replaced by skin from the homonymous part of her vagina, provided her old-fashioned Sicilian husband thinks it's from another organ.
Naomi Gaines
Dissatisfied ex-liposuction-patient Bobbi Broderick scares others away even right in the doctors's waiting room, demanding a public admission on TV, or she'll sue them. Life coach Ava Moore 'professionally motivates' Matt between the sheets, to the anger of her own, allegedly jealous, also 16-year old son Adrian, who she regrets not to have aborted. Sean and Julia are not amused when Matt sets off the brand new alarm, sneaking in at night after 'studying together with Adrian' they didn't even know existed. Serial raper-mutilator 'the Carver' sends the doctors both patients, now model Naomi Gaines, and scary packages. Christian decides to offer his alternative pro-bono story to bitch Bobbi's journalist, Andrea Hall, who happily lands in his bed before she even knows his professionally relevant name and succeeds. When the McNamaras invite the Moores for dinner, Adrian sort of hints at the truth and kisses startled Matt in the kitchen, then blurts it out after Ava lies never to have denied him anything; Julia throws the child-rapist out. Bobbi now promises a class-action law-suit, but after Naomi sides with the doctors admits she herself did everything wrong, even missed her job interview on purpose. When Matt goes break up with Ava, she tells him about Julia's infidelity; finding ma searching his room 'you'll have to earn your privacy now' he makes her confess Christian sired him, but when Sean walks in doesn't tell but falls in daddy's arms after confessing his just ended relationship with Ava.
Agatha Ripp
The doctors accept to operate pro bono the whore Agatha Ripp, who claims her greatest sin was to have inflicted stigmata to herself and asks them to convince St. Olav shelter and the parish they are fake. The surgeons must reassure pregnant Liz and Julia, who even gets psychosomatic shingles. When the news lands them with a baby's congenital caudal appendix, also pro bono, Sean fails to convince the archdiocese's Father Maley Agatha can't have miraculous stigmata. While still recovering from the operation, Agatha gets unexplained new ones, now claiming they're real but she doesn't want them and the blood is not hers. When Julia tells him Christian is Matt's father, Sean is shattered, furious, throws her out and attacks his partner. Liz also has shattering news for Christian.
Then Agatha Rose and Raven Rosenberg
After finding out Christian and Julia are Matt's biological parents, Sean is hell-bent to dissolve his partnerships with both, despite professional advice it would be utter disaster for the surgery. Matt and Sean remain tight as son and dad. The doctors still fly together for what is now likely to be their last case, a historical pro bono multi-disciplinary operation: the oldest Siamese twins ever separated, teenage sisters Rose and Raven Rosenberg, who are joined at the forehead. Neither dreamed of being alone, but it's necessary to give one sister chemotherapy. Having to share a dorm room makes the partners reminisce their past and complementarity. Julia's "I gave everything up for you" routine has lost all effect on Matt, who feels no connection with her and even returns to Ava, so she calls the 'fathers', but neither wants to make sonny study hard now. The operation kills Raven, Rose seems to have lost the will to live and dies too. Sean hits the Scotch and pays prostitute Renée for a threesome with 'Julia' and Christian, the one thing they never quite shared. Only now, mother Rosenberg admits neither girl wanted to survive alone; the sisters are re-joined posthumously. The sole survivor is- the surgeons' partnership, Sean has come to his senses.
Kimber Henry
Ike Connors is a unique client: he is an author who writes books about extreme experiences, and his newest book contract is for the experience of having breasts, which the plastic surgeons must create, just like his wife's, whose mastectomy made them aware how important boobs are for the female (self-) image. Sean is ready to continue working with Christian as they need each-other business-wise, but won't consider forgiving or understanding Julia to any degree, so he doesn't want her to disturb daughter Annie's routine. Christian's ex, actress Kimber Henry, has finally become a porno starlet and consults the doctors to correct the vagina on a sex doll after her image which should be a financial goldmine; Sean takes the prototype home and has sex with both the silicon - and the natural versions. After his operation was a success, Ike changes his mind because of the pain and as it feels lesbian, to his wife's fury. Julia picks up a non-local businessman Roger in a bar, but he is a masochist who took her for a hooker; now Sean rescues her but returns straight to Kimber's doll.
Natasha Charles
Natasha Charles is an unusual patient- her whole body is attractive, but since birth her eyes are blind, covered with a 'scary' white-blue membrane, as Christian puts it when she asks him to make her attractive to him, so the doctors operate to implant artificial eyes from an expert. Afterward Christian follows her when he hears she has an Internet date, finds out that's a blind man who still asks him whether she's attractive and even dumps her when he lies she's much older; so he's happy to fill in and enjoys sex with a woman who can't be after his gorgeous body. Meanwhile Sean remains merciless on Julia, who has her breasts enlarged by a female surgeon and gets unwanted visitors- lice on Annie's head from some classmate and her own mother Erica, who tries in vain to make Sean and Christian do an intervention with Julia and rushes off again to another lecture; when Sean is unmoved by her improved balcony she overdoes her painkillers and has a bad fall trough a glass wall...
Julia McNamara
Now Julia McNamara has crashed trough a glass wall after having OD'ed out of frustration with her shattered family since Sean knows Matt isn't his biological son, she is dreaming an alternative reality, where just about everything is different and everyone plays an amended part, e.g. Christian Troy is a loyal husband- and still it is far from perfect for her.
Oona Wentworth
Christian and Sean discover a maid's horribly mutilated forehead is the result of the systematical sale of 'Bobotox', a scandalous 'cheap Botox', by their former associate Dr. Merril Bobolit, who is now a drug addict; Christian gets him into addicts anonymous, where he falls in love but is rejected as a loser. Matt sees how Adrian Moore helps himself to lots of opiates from his mother Ava's stock, to sell to school kids, hiding it in his jacket; the boys fight, and the bitter old lady principal won't budge for Ava's threats or Christian's offer to donate to the school, but accepts plastic surgery. Shortly after, Adrian urinates in a soap dispenser at school just before Matt will use it, but innocent school mate Trevor Hayes suffers the same fate- his parents demand punishment, and since Matt doesn't rat, Sean, who has claimed his parental role back from Christian, makes him come straight from school to his office 'for meaningless chores'. Ava punishes Adrian by giving all his clothes to her Salvadorian new toy-boy, Alfonso Tehon Jr. Now Bobolit and his lay partner, a massage parlor owner gone bust, even operate, but the patient dies; they plan to dispose of the cut-up corpse; Christian accidentally finds out and is knocked out and strapped down, about to have his face 'stolen' by the madman, who fortunately passes out trying to operate on himself simultaneously. Matt uses his surgery chores to make up with Sean. Adrian and Ava make up and pass straight to incestuous kissing.
Trudy Nye
Because of the loud music Christian's blind girl friend Natasha Charles notices nothing when two brats first moon her and then steal half of his sports car while she's waiting in it for him to return from the video store. Ava Moore continues to exasperate Adrian. Kimber Henry believes a palm reader that prolonging her hand lines can improve her faith and is angrily embarrassed when Julia and her date Kevin Hodgekiss greet Sean and her in the restaurant where the then couple celebrated Valentines day last year; in bed Sean promises her the absurd operation. Trudy Nye has the doctors repair her nose, broken 13 years ago by her about to be released from jail abusive husband Stan, who semi-accidentally killed their five-year old son Tyler for leaving toys all over the house; when the reconciled couple returns to have his face made unrecognizable, Christian refuses any form of complicity. Christian stands in for Sean to operate Kimber, and gets her to have sex there, so Sean can walk in on them end break up with her as he wanted. When Sean and Julia confront Ava about her incest while doing it with Matt, she says Adrian was given up for adoption because of a mental handicap; he runs away. Christian dumps Natasha after she forgave him 'too nobly' for fucking Kimber. Trudy returns to have her newly broken nose fixed, pregnant but denying Stans guilt.
Sean McNamara
Christians hedonistic world comes crashing down when his crazy sex-addicted ex Gina calls him because she has tested positive for HIV, so he fears to be positive too. After confiding into Sean, he gathers the courage to inform his numerous sexual contacts who need to be tested too, including baby Wilbur and his father. Kimber is surprisingly understanding, even tells him he won't be alone and abandoned by everyone. Sean is attacked by a masked unknown, drugged and slashed in the face. Julia helps nurse him but stays with Kevin. It's probably the doing of the madman who attacked a girl at Matts school, and her parents asks him to help personally, which doubtlessly would arouse his utter anger; yet he operates her. Christian visits Gina in a crappy clinic, and finds she's not on the necessary cocktail, lacking health insurance; he can now tell her to have tested negative himself.
Joan Rivers
Joan Alexandra Molinsky asks the surgeons to undo all the plastic surgery she ever had as actress Joan Rivers, being ashamed she started the fashion of plastic surgery, especially to her lovely loving grandson Cooper, and pointing out it's a superb publicity stunt for her and the surgery firm. Ava says even besides Matt in bed, she'll never be happy again as long as people judge her; he proposes to start again in Paris and promises her anti-depression drugs- Christian surprises him stealing and sees trough his pretense it's for him; when he confronts her, she dares him into sexual power play, but he suddenly walks out during a fuck and tells Sean Ava is a male transsexual, which explains his shopping list for Matt who risks irreparable psychological damage if he finds out. The serial slasher's victims seem butchered even worse; it gives Sean nightmare hallucinations, as if talking to Colombian drug mafioso Escobar Gallardo who says he must kill the slasher, so he gets a better security firm. Adrian buys a gutting knife. The surgeons fly to Cara Nelson in Baltimore, searching the only surgeon who could have done a perfect sex change on Ava 17 years ago, pretending she's their patient, and learn her file was passed on to a colleague, retired Dr. Barett Moore, who now breads orchids and tells them Avery Tanner was a pretty gay boy who actually lusted him enough to choose a sex change, but the following marriage was a lie despite Adrian's birth. Julia tries threatening Ava to back off, and learns her price is the finishing touch-vaginal operation, which the doctors give her- with Barett, to her delighted surprise. Afterwards she tells Matt he's a hopeless boy needing a mother and refuses to go to Paris with him. Joan doesn't even like the idea of seeing what her inverse operations idea would make her look like, the computer simulation makes her change her mind- to another face-lift. While Ava is packing to leave alone, Adrian turns up; she fails talking and kissing him into joining her to Paris: being lied to too often, he stabs- himself to death. Matt is welcomed back home, Sean sleeps with a loaded revolver in hand, but the slasher surprises Christian...